The data flow and systems involved in our quantitative lung processes are are:

1. Image Exchange: The system is in charge of transmitting images between the study sites and the ACIL Private Network. The system should be secure and complied with HIPAA. ACIL uses Ambra as vendor to fulfill these tasks unless the study sponsored provides an alternative solution that fulfill all the privacy and PHI requirements required by ACIL and BWH. ACIL can also receive data through courier mail as long as the data is de-identified by the sites.
2. Data Ingestion Workstation: ACIL Workstation that interfaces with the exchange system to retrieve image studies, check image integrity and PHI compliance, harmonize the naming, registering the study in the ACIL DB and transfer to the ACIL study archiving in MAD3.
3. RFA Storage: This storage is used by the Data Ingestion Workstation for the secure archiving of data retrieved from the Image Exchange.
4. MAD3: This storage archives the images and by-product results related to each image for a particular study.
5. ERISOne Computing Cluster: Computing environment where the image analysis and biomarker extraction pipeline take place as part of the process described in our standarized operating procedures.
6. ACIL DB: Database infrastructure and storage that records the study participant, associated image/s, quality control status and results.
7. Quality Control Workstation: All our processed follow a strict quality control assessment as part of our standarized approaches. Deviations are registered in our internal database and corrective actions are put in place.
8. Reporting Workstation: Workstation employed by the PI and PA to perform the data compilation and reporting needs for the study according to the Study Sponsor requirements and specifications.