Applied Chest Imaging Laboratory

Airway Inspector: a chest imaging biomarker software platform for COPD

Grant support: 1R01HL116931-01

PI: Dr. Raul San Jose Estepar

Project Information:

The goal of this project is to refactor and develop Airway Inspector as a platform for image-based COPD research. The software platform will be used to create workflows that will be integrated in Slicer 4 for their deployment in the clinical studies.

People Involved:

Dr. Alejandro A. Diaz, Dr. Rola Harmouche, Jorge Onieva, Dr. James Ross, Dr. Raúl San José Estépar, Dr. Gonzalo Vegas Sanchez-Ferrero

Publications:

Castaldi PJ, Cho MH, San José Estépar R, McDonald M-LN, Laird N, Beaty TH, Washko G, Crapo JD, Silverman EK. Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns. Am J Respir Crit Care Med 2014;190(4):399-409. Abstract

Castaldi PJ, San José Estépar R, Mendoza CS, Hersh CP, Laird N, Crapo JD, Lynch DA, Silverman EK, Washko GR. Distinct quantitative computed tomography emphysema patterns are associated with physiology and function in smokers. Am J Respir Crit Care Med 2013;188(9):1083-90. Abstract