@article {1433660,
	title = {Pulmonary cysts identified on chest CT: are they part of aging change or of clinical significance?},
	journal = {Thorax},
	volume = {70},
	number = {12},
	year = {2015},
	month = {2015 Dec},
	pages = {1156-62},
	abstract = {OBJECTIVE: To investigate the prevalence and natural course of pulmonary cysts in a population-based cohort and to describe the CT image characteristics in association with participant demographics and pulmonary functions.

MATERIALS AND METHODS: Chest CT scans of 2633 participants (mean age 59.2 years; 50\% female) of the Framingham Heart Study (FHS) were visually evaluated for the presence of pulmonary cysts and their image characteristics. These findings were correlated with participant demographics and results of pulmonary function tests as well as the presence of emphysema independently detected on CT. The interval change was investigated by comparison with previous CT scans (median interval 6.1 years).

RESULTS: Pulmonary cysts were seen in 7.6\% (95\% CI 6.6\% to 8.7\%; 200/2633). They were not observed in participants younger than 40 years old, and the prevalence increased with age. Multiple cysts (at least five) were seen in 0.9\% of all participants. Participants with pulmonary cysts showed significantly lower body mass index (BMI) (p,
	keywords = {Adult, Age Factors, Aged, Aged, 80 and over, Aging, Asymptomatic Diseases, Cysts, Female, Humans, Lung Diseases, Male, Middle Aged, Respiratory Function Tests, Tomography, X-Ray Computed},
	issn = {1468-3296},
	doi = {10.1136/thoraxjnl-2015-207653},
	author = {Araki, Tetsuro and Nishino, Mizuki and Gao, Wei and Dupuis, Jos{\'e}e and Putman, Rachel K and Washko, George R and Hunninghake, Gary M and O{\textquoteright}Connor, George T and Hatabu, Hiroto}
}