@article {1433605,
	title = {Pleural abnormalities in the Framingham Heart Study: prevalence and CT image features},
	journal = {Occup Environ Med},
	volume = {74},
	number = {10},
	year = {2017},
	month = {2017 10},
	pages = {756-761},
	abstract = {BACKGROUND: The prevalence of pleural abnormalities in the general population is an epidemiologically important index of asbestos exposure, which has not been investigated since a radiography-based study in 1980.

METHODS: We examined 2633 chest CT scans (mean 59.2 years, 50\% female) from the Framingham Heart Study (FHS) for the presence and image characteristics of pleural plaques and diffuse pleural thickening. Demographics and pulmonary function were stratified by the presence of pleural abnormalities in association with interstitial lung abnormalities.

RESULTS: Pleural abnormalities were present in 1.5\% (95\% CI 1.1\% to 2.1\%). Pleural lesions were most commonly bilateral (90.0\%), multiple (77.5\%), calcified (97.5\%) and commonly involved posterior (lower: 92.5\%, middle: 87.5\%), anterior (upper: 77.5\%, middle: 77.5\%) and diaphragmatic areas (72.5\%). Participants with pleural abnormalities were significantly older (75.7 years, p ,
	keywords = {Adult, Aged, Aged, 80 and over, Asbestos, Environmental Exposure, Female, Humans, Lung, Male, Middle Aged, Pleura, Pleural Diseases, Prevalence, Radiography, Thoracic, Tomography, X-Ray Computed},
	issn = {1470-7926},
	doi = {10.1136/oemed-2016-104178},
	author = {Araki, Tetsuro and Yanagawa, Masahiro and Sun, Fangui Jenny and Dupuis, Jos{\'e}e and Nishino, Mizuki and Yamada, Yoshitake and Washko, George R and Christiani, David C and Tomiyama, Noriyuki and O{\textquoteright}Connor, George T and Hunninghake, Gary M and Hatabu, Hiroto}
}