@article {1433672,
	title = {Paraseptal emphysema: Prevalence and distribution on CT and association with interstitial lung abnormalities},
	journal = {Eur J Radiol},
	volume = {84},
	number = {7},
	year = {2015},
	month = {2015 Jul},
	pages = {1413-8},
	abstract = {OBJECTIVE: To investigate the prevalence and distribution of paraseptal emphysema on chest CT images in the Framingham Heart Study (FHS) population, and assess its impact on pulmonary function. Also pursued was the association with interstitial lung abnormalities.

MATERIALS AND METHODS: We assessed 2633 participants in the FHS for paraseptal emphysema on chest CT. Characteristics of the participants, including age, sex, smoking status, clinical symptoms, and results of pulmonary function tests, were compared between those with and without paraseptal emphysema. The association between paraseptal emphysema and interstitial lung abnormalities was investigated.

RESULTS: Of the 2633 participants, 86 (3\%) had pure paraseptal emphysema (defined as paraseptal emphysema with no other subtypes of emphysema other than paraseptal emphysema or a very few centrilobular emphysema involved) in at least one lung zone. The upper zone of the lungs was almost always involved. Compared to the participants without paraseptal emphysema, those with pure paraseptal emphysema were significantly older, and were more frequently male and smokers (mean 64 years, 71\% male, mean 36 pack-years, P,
	keywords = {Age Factors, Aged, Carbon Monoxide, Female, Humans, Lung, Male, Middle Aged, Prevalence, Pulmonary Emphysema, Respiratory Function Tests, Sex Factors, Smoking, Tomography, X-Ray Computed},
	issn = {1872-7727},
	doi = {10.1016/j.ejrad.2015.03.010},
	author = {Araki, Tetsuro and Nishino, Mizuki and Zazueta, Oscar E and Gao, Wei and Dupuis, Jos{\'e}e and Okajima, Yuka and Latourelle, Jeanne C and Rosas, Ivan O and Murakami, Takamichi and O{\textquoteright}Connor, George T and Washko, George R and Hunninghake, Gary M and Hatabu, Hiroto}
}