@article {1433615, title = {Association between Cardiorespiratory Fitness and Lung Health from Young Adulthood to Middle Age}, journal = {Am J Respir Crit Care Med}, volume = {195}, number = {9}, year = {2017}, month = {2017 05 01}, pages = {1236-1243}, abstract = {RATIONALE: Beyond the risks of smoking, there are limited data on factors associated with change in lung function over time. OBJECTIVES: To determine whether cardiorespiratory fitness was longitudinally associated with preservation of lung health. METHODS: Prospective data were collected from 3,332 participants in the Coronary Artery Risk Development in Young Adults study aged 18-30 in 1985 who underwent treadmill exercise testing at baseline visit, and 2,735 participants with a second treadmill test 20 years later. The association between cardiorespiratory fitness and covariate adjusted decline in lung function was evaluated. MEASUREMENTS AND MAIN RESULTS: Higher baseline fitness was associated with less decline in lung function. When adjusted for age, height, race-sex group, peak lung function, and years from peak lung function, each additional minute of treadmill duration was associated with 1.00 ml/yr less decline in FEV (P , keywords = {Adolescent, Adult, Age Factors, Cardiorespiratory Fitness, Exercise Test, Forced Expiratory Volume, Health Status, Humans, Lung, Middle Aged, Prospective Studies, Respiratory Function Tests, Sex Factors, Vital Capacity, Young Adult}, issn = {1535-4970}, doi = {10.1164/rccm.201610-2089OC}, author = {Benck, Lillian R and Cuttica, Michael J and Colangelo, Laura A and Sidney, Stephen and Dransfield, Mark T and Mannino, David M and Jacobs, David R and Lewis, Cora E and Zhu, Na and Washko, George R and Liu, Kiang and Carnethon, Mercedes R and Kalhan, Ravi} }