@article {1433684,
	title = {An official American Thoracic Society/European Respiratory Society statement: research questions in COPD},
	journal = {Eur Respir J},
	volume = {45},
	number = {4},
	year = {2015},
	month = {2015 Apr},
	pages = {879-905},
	abstract = {Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality, and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) research statement is to describe evidence related to diagnosis, assessment and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers, and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers, and patient advocates believe will have the greatest impact on patient-centred outcomes. },
	keywords = {Biomedical Research, Disease Management, Europe, Evidence-Based Medicine, Female, Humans, Male, Practice Guidelines as Topic, Prognosis, Pulmonary Disease, Chronic Obstructive, Societies, Medical, Surveys and Questionnaires, Survival Analysis, United States},
	issn = {1399-3003},
	doi = {10.1183/09031936.00009015},
	author = {Celli, Bartolome R and Decramer, Marc and Wedzicha, Jadwiga A and Wilson, Kevin C and Agust{\'\i}, Alvar and Criner, Gerard J and MacNee, William and Make, Barry J and Rennard, Stephen I and Stockley, Robert A and Vogelmeier, Claus and Anzueto, Antonio and Au, David H and Barnes, Peter J and Burgel, Pierre-Regis and Calverley, Peter M and Casanova, Ciro and Clini, Enrico M and Cooper, Christopher B and Coxson, Harvey O and Dusser, Daniel J and Fabbri, Leonardo M and Fahy, Bonnie and Ferguson, Gary T and Fisher, Andrew and Fletcher, Monica J and Hayot, Maurice and Hurst, John R and Jones, Paul W and Mahler, Donald A and Maltais, Fran{\c c}ois and Mannino, David M and Martinez, Fernando J and Miravitlles, Marc and Meek, Paula M and Papi, Alberto and Rabe, Klaus F and Roche, Nicolas and Sciurba, Frank C and Sethi, Sanjay and Siafakas, Nikos and Sin, Don D and Soriano, Joan B and Stoller, James K and Tashkin, Donald P and Troosters, Thierry and Verleden, Geert M and Verschakelen, Johny and Vestbo, Jorgen and Walsh, John W and Washko, George R and Wise, Robert A and Wouters, Emiel F M and ZuWallack, Richard L}
}