@article {1433699, title = {Airway wall thickness is increased in COPD patients with bronchodilator responsiveness}, journal = {Respir Res}, volume = {15}, year = {2014}, month = {2014 Aug 08}, pages = {84}, abstract = {RATIONALE: Bronchodilator responsiveness (BDR) is a common but variable phenomenon in COPD. The CT characteristics of airway dimensions that differentiate COPD subjects with BDR from those without BDR have not been well described. We aimed to assess airway dimensions in COPD subjects with and without BDR. METHODS: We analyzed subjects with GOLD 1-4 disease in the COPDGene{\textregistered} study who had CT airway analysis. We divided patients into two groups: BDR + (post bronchodilator ΔFEV1 >= 10\%) and BDR-(post bronchodilator ΔFEV1 , keywords = {Aged, Aged, 80 and over, Bronchodilator Agents, Female, Humans, Lung, Male, Middle Aged, Pulmonary Disease, Chronic Obstructive, Radiography}, issn = {1465-993X}, doi = {10.1186/s12931-014-0084-3}, author = {Kim, Victor and Desai, Parag and Newell, John D and Make, Barry J and Washko, George R and Silverman, Edwin K and Crapo, James D and Bhatt, Surya P and Criner, Gerard J} }